Multicentric lymphoma is the most common canine cancer.
Multicentric lymphoma is the most common form of lymphoma, or cancer, in dogs. It usually is seen first in the lymph nodes and in middle-aged and older dogs.
Definition
A lymphoma originates in the lymphocytes. These are the white blood cells produced as part of the immune system that protect the body from infection. Multicentric lymphoma usually starts in the animal's lymph nodes or organs associated with the immune system, such as the spleen.
Causes
Veterinarians do not know the exact cause, but believe that viruses, bacteria and chemicals may be possible factors. An impaired immune function appears to be strongly implicated in the development of the condition.
Symptoms
In dogs the most common symptom is enlarged lymph nodes. These are firm to the touch but not painful to the animal. Other symptoms are loss of appetite, lethargy and increased thirst.
Diagnosis
A biopsy is necessary for diagnosis. The vet performs a needle, incisional or excisional biopsy while the animal is sedated. Blood tests, x-rays and bone marrow also are likely to be tested.
Treatment
Chemotherapy administered by intravenous injection is recommended for dogs. A combination of drugs given over weeks or months offers the highest rates of remission. Dogs tolerate chemotherapy much better than humans and are less likely to suffer its side effects.
Tags: lymph nodes, most common, Multicentric lymphoma, immune system, lymphoma most
